PhD Scholars
His research interests are focused on exploring Ruthenium, Rhenium, and Iridium complexes as efficient agents for chemodynamic therapy. Emphasis is placed on designing redox-active metal complexes capable of generating reactive oxygen species within the tumor microenvironment to induce selective cancer cell death. Investigations are carried out to understand their catalytic mechanisms, cellular uptake, and interaction with biomolecules. Efforts are directed toward enhancing therapeutic selectivity, biocompatibility, and synergistic effects with other treatment modalities for improved anticancer efficacy.
His research focuses on the development of dual-functioning monometallic Ru(II), Ir(III), and Re(I) complexes for chemodynamic therapy. These complexes are designed to selectively target mitochondria, leading to mitochondrial dysfunction and subsequent cell death. His studies have demonstrated that the complexes can induce multiple cell death pathways, including apoptosis, ferroptosis, and mitophagy. In addition, he has also contributed to the field of photodynamic therapy (PDT), exploring light-activated mechanisms for enhanced anticancer activity.
His research interests are focused on the design and development of Ruthenium, Iridium, and Rhenium complexes as potent photosensitizers for photodynamic therapy. Emphasis is placed on engineering their photophysical and photochemical properties to achieve efficient light absorption, singlet oxygen generation, and targeted tumor selectivity. Studies are conducted to elucidate their photoinduced cytotoxic mechanisms and biological interactions. Efforts are directed toward optimizing their stability, biocompatibility, and therapeutic efficiency for precise and controllable cancer treatment under light activation.
Her research interest includes Organometallic and Bioinorganic Chemistry focusing on "Development of Iridium(III) and Praseodymium(III) Complexes as Photosensitizers for Photodynamic Therapy". She is particularly interested in developing cyclometalated Iridium(III) complexes with an aim to contribute to the development of next-generation PDT agents with enhanced tumor specificity, deeper tissue penetration, and reduced side effects compared to conventional chemotherapeutics.
Her research interests are focused on the synthesis and mechanistic exploration of cyclometalated Iridium(III) complexes as potent phototheranostic agents. Emphasis is placed on developing multifunctional systems capable of simultaneous cancer imaging and therapy through light-triggered mechanisms. Studies are conducted to elucidate their photophysical, photochemical, and biological properties, enabling precise tumor localization and selective cytotoxicity. Efforts are directed toward optimizing their structure–activity relationship to enhance photoresponsiveness, biocompatibility, and therapeutic efficiency in targeted cancer treatment.
His research interests are focused on the synthesis and structural design of organometallic compounds for biomedical applications. Special emphasis is placed on the development of advanced nanocarrier systems for targeted and controlled anticancer drug delivery. Investigations are carried out to understand the molecular interactions of these metal-based systems with biological targets, aiming to enhance therapeutic selectivity, minimize side effects, and develop efficient photoresponsive platforms for next-generation cancer treatment.
Master's Students
She is pursuing her Master’s in Chemistry with a specialization in Organic Chemistry at VIT, Vellore. Her research focuses on synthesizing and characterizing Iridium and Rhenium-based heterocyclic organometallic complexes for anticancer applications. She is interested in studying their interactions with biomolecules like DNA, HSA, and GSH. Her upcoming work involves designing pyridinium-based complexes to enhance biological activity and develop effective, selective metal-based anticancer agents.
He is a MSc Part 2 student, specialising in Organic Chemistry. His research interests are focused on the synthesis, characterization, and photophysical investigation of di-imidazo-based extended heterocycles. Emphasis is placed on understanding their structural, electronic, and optical properties to explore potential applications in materials science and bioinorganic chemistry. Current efforts involve designing novel derivatives with enhanced functionality and photophysical performance.
She is a MSc Part 2 student specializing in Organic Chemistry. My project focuses on the "Synthesis, characterization, and study of photophysical properties of triazole-based extended heterocycles using click chemistry". Through this research, she aim to explore their potential applications in photochemical systems.
He is pursuing MSc in Chemistry at VIT Vellore. His research interests focus on palladium-catalyzed cross-coupling methodologies for constructing complex organic molecules. Emphasis is on Suzuki and Sonogashira reactions to form selective carbon–carbon bonds. Current work involves applying these methods synergistically for the targeted synthesis of novel organic derivatives, demonstrating their efficiency, selectivity, and relevance in modern organic chemistry.
She is pursuing MSc in Chemistry at VIT Vellore. Her research interests focus on the Suzuki cross-coupling reaction as a versatile method for constructing complex organic frameworks. Emphasis is on optimizing catalysts and conditions for efficient carbon–carbon bond formation between organoboron reagents and aryl halides. Current work involves synthesizing novel biaryl and conjugated compounds, highlighting the reaction’s selectivity and utility.
She is pursuing MSc in Chemistry at VIT Vellore. Her research focuses on designing and developing Ru/Ir-based artificial metalloenzymes as novel catalytic systems for targeted cancer therapy. These hybrid bioinorganic complexes aim to combine the selectivity of enzymes with the therapeutic potential of metal centers, enabling site-specific activation of prodrugs and minimizing toxicity to healthy cells.